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N3-PEG5-aldehyde [CAS 2566404-73-5]
N3-PEG5-aldehyde [CAS 2566404-73-5]
SKU:QM-0062871
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Product Details
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Description
N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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CAS Number
[2566404-73-5]
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Molecular Formula
C20H30N4O7
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Molecular Weight
438.47
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Smiles
[H]C(C(C=C1)=CC=C1C(NCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O
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Target
ADC Linker
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Isoform
Cleavable Linker
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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N3-PEG5-aldehyde [CAS 2566404-73-5]
N3-PEG5-aldehyde is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.