N3-Ph-NHS ester [CAS 53053-08-0]
N3-Ph-NHS ester [CAS 53053-08-0]
SKU:QM-0141960-01
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Product Details
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Description
N3-Ph-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-Ph-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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CAS Number
[53053-08-0]
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Molecular Formula
C11H8N4O4
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Molecular Weight
260.21
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Smiles
O=C(ON1C(CCC1=O)=O)C2=CC=C(N=[N+]=[N-])C=C2
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Target
ADC Linker
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Isoform
Non-cleavable Linker
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Purity
99.88
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Solubility
DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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N3-Ph-NHS ester [CAS 53053-08-0]
N3-Ph-NHS ester is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.