N6-Methyladenosine (Standard) [CAS 1867-73-8]
N6-Methyladenosine (Standard) [CAS 1867-73-8]
SKU:QM-0162025-01
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Product Details
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Description
N6-Methyladenosine (Standard) is the analytical standard of N6-Methyladenosine. This product is intended for research and analytical applications. N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities. In Vitro: N6-methyladenosine (m6A) is selectively recognized by the human YTH domain family 2 (YTHDF2) protein to regulate mRNA degradation. N6-methyladenosine (m6A), a prevalent internal modification in the messenger RNA of all eukaryotes, is post-transcriptionally installed by m6A methyltransferase (e.g., MT-A70) within the consensus sequence of G (m6A) C (70%) or A (m6A) C (30%) . N6-methyladenosine (m6A) -containing RNAs are greatly enriched in the YTHDF-bound portion and diminished in the flow-through portion[1]. N6-methyladenosine (m6A), the most abundant internal RNA modification, functions in diverse biological processes, including regulation of embryonic stem cell self-renewal and differentiation. N6-methyladenosine (m6A) is a large protein complex, consisting in part of methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14) catalytic subunits[2].
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CAS Number
[1867-73-8]
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Molecular Formula
C11H15N5O4
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Molecular Weight
281.27
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Smiles
O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C3=C(N=C2)C(NC)=NC=N3
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Target
Endogenous Metabolite; Influenza Virus; Reference Standards
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Purity
99.65
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Storage Conditions
4°C, sealed storage, away from light and moisture
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Shipping Conditions
Blue Ice
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N6-Methyladenosine (Standard) [CAS 1867-73-8]
N6-Methyladenosine (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.