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Navlimetostat [CAS 2630904-45-7]

Navlimetostat [CAS 2630904-45-7]

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QM-0076823-01

£313.65 GBP
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Product Details

  • Description

    Navlimetostat is a potent, orally active, selective PRMT5-MTA complex inhibitor, with IC50 of 3.6 and 20.5 nM for PRMT5-MTA and PRMT5. Navlimetostat binds to the PRMT5-MTA complex, with KD value of 0.14 pM. Navlimetostat shows antineoplastic activity in vitro and in vivo, and can be used for cancer study[1][2].

  • CAS Number

    [2630904-45-7]

  • Molecular Formula

    C23H18ClFN6O2

  • Molecular Weight

    464.88

  • Smiles

    FC1=C(C=C(C(C#N)=[C@]1[C@]2=C(C3=CC=C4C(C(CN)=NNC4=O)=C3)C=NN2C)OC5CC5)Cl

  • Target

    Histone Methyltransferase

  • Isoform

    PRMT5

  • Purity

    99.4

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319

  • Precautions

    H302, H315, H319
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Variant Variant total Quantity Price Variant total
1 mgQM-0076823-01
1 mgQM-0076823-01
£313.65/ea		 £0.00
£313.65/ea £0.00
5 mgQM-0076823-02
5 mgQM-0076823-02
£1,128.92/ea		 £0.00
£1,128.92/ea £0.00
10 mM - 1 mLQM-0076823-03
10 mM - 1 mLQM-0076823-03
£1,154.43/ea		 £0.00
£1,154.43/ea £0.00
10 mgQM-0076823-04
10 mgQM-0076823-04
£1,505.57/ea		 £0.00
£1,505.57/ea £0.00
25 mgQM-0076823-05
25 mgQM-0076823-05
£2,460.56/ea		 £0.00
£2,460.56/ea £0.00
50 mgQM-0076823-06
50 mgQM-0076823-06
£3,438.64/ea		 £0.00
£3,438.64/ea £0.00
100 mgQM-0076823-07
100 mgQM-0076823-07
£4,820.09/ea		 £0.00
£4,820.09/ea £0.00
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Navlimetostat [CAS 2630904-45-7]

Navlimetostat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.