Nefazodone-d6 (hydrochloride)
Nefazodone-d6 (hydrochloride)
SKU:QM-0159746-01
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Product Details
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Description
Nefazodone-d6 (hydrochloride) is the deuterium labeled Nefazodone hydrochloride. Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A (Ki=5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake (IC50 of 290 and 300 nM, respectively) . Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity[1][2].
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Molecular Formula
C25H27D6Cl2N5O2
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Molecular Weight
512.5
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Smiles
O=C1N(C([2H])([2H])C([2H])([2H])C([2H])([2H])N2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4.[H]Cl
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Target
5-HT Receptor; Adrenergic Receptor; Isotope-Labeled Compounds
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Isoform
5-HT2 Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Nefazodone-d6 (hydrochloride)
Nefazodone-d6 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.