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Neflamapimod [CAS 209410-46-8]

Neflamapimod [CAS 209410-46-8]

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QM-0077478-01

£89.13 GBP
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Product Details

  • Description

    Neflamapimod (VX-745) is a potent, blood-brain barrier penetrant, highly selective inhibitor of p38α inhibitor with an IC50 for p38α of 10 nM and for p38β of 220 nM. Neflamapimod (VX-745) possesses anti-inflammatory activity.

  • CAS Number

    [209410-46-8]

  • Molecular Formula

    C19H9Cl2F2N3OS

  • Molecular Weight

    436.26

  • Smiles

    O=C1N=CN(C(C=C2)=C1C3=C(Cl)C=CC=C3Cl)N=C2SC4=CC=C(F)C=C4F

  • Target

    Autophagy; p38 MAPK

  • Isoform

    P38α; p38β

  • Concentration

    10mM

  • Purity

    99.32

  • Solubility

    DMSO : 12.5 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0077478-01
5 mgQM-0077478-01
£89.13/ea		 £0.00
£89.13/ea £0.00
10 mM - 1 mLQM-0077478-02
10 mM - 1 mLQM-0077478-02
£94.75/ea		 £0.00
£94.75/ea £0.00
10 mgQM-0077478-03
10 mgQM-0077478-03
£127.38/ea		 £0.00
£127.38/ea £0.00
50 mgQM-0077478-04
50 mgQM-0077478-04
£381.69/ea		 £0.00
£381.69/ea £0.00
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Neflamapimod [CAS 209410-46-8]

Neflamapimod is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.