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Nevanimibe hydrochloride [CAS 133825-81-7]

Nevanimibe hydrochloride [CAS 133825-81-7]

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SKU:QM-0079279-01

£376.83 GBP
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  • Description

    Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer[1].

  • CAS Number

    [133825-81-7]

  • Molecular Formula

    C27H40ClN3O

  • Molecular Weight

    458.08

  • Smiles

    O=C(NCC1(C2=CC=C(N(C)C)C=C2)CCCC1)NC3=C(C(C)C)C=CC=C3C(C)C.[H]Cl

  • Target

    Acyltransferase; Apoptosis

  • Isoform

    ACAT1; ACAT2

  • Purity

    99.49

  • Solubility

    DMSO : 41.67 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

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Variant Variant total Quantity Price Variant total
5 mgQM-0079279-01
5 mgQM-0079279-01
£376.83/ea
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10 mM - 1 mLQM-0079279-02
10 mM - 1 mLQM-0079279-02
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10 mgQM-0079279-03
10 mgQM-0079279-03
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50 mgQM-0079279-04
50 mgQM-0079279-04
£966.11/ea
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£966.11/ea £0.00
100 mgQM-0079279-05
100 mgQM-0079279-05
£1,241.91/ea
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Nevanimibe hydrochloride [CAS 133825-81-7]

Nevanimibe hydrochloride is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.