Nevanimibe hydrochloride (Standard) [CAS 133825-81-7]
Nevanimibe hydrochloride (Standard) [CAS 133825-81-7]
SKU:QM-0001799-01
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Product Details
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Description
Nevanimibe hydrochloride (Standard) is the analytical standard of Nevanimibe hydrochloride. This product is intended for research and analytical applications. Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer[1].
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CAS Number
[133825-81-7]
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Molecular Formula
C27H40ClN3O
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Molecular Weight
458.08
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Smiles
O=C(NCC1(C2=CC=C(N(C)C)C=C2)CCCC1)NC3=C(C(C)C)C=CC=C3C(C)C.[H]Cl
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Target
Acyltransferase; Apoptosis; Reference Standards
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Shipping Conditions
Room temperature
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Nevanimibe hydrochloride (Standard) [CAS 133825-81-7]
Nevanimibe hydrochloride (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.