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NF-κB/MAPK-IN-1 [CAS 2413940-56-2]

NF-κB/MAPK-IN-1 [CAS 2413940-56-2]

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QM-0149489-01

£188.51 GBP
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Product Details

  • Description

    NF-κB/MAPK-IN-1 (compound 11a) is a potent inhibitor of NF-κB and MAPK pathway. NF-κB/MAPK-IN-1 shows inhibitory activity against NO production, with an IC50 of 6.96 µM. NF-κB/MAPK-IN-1 suppresses LPS-induced iNOS, COX-2, ERΚ and P38 signaling activation. NF-κB/MAPK-IN-1 can prevent LPS induced inflammatory response in macrophages. NF-κB/MAPK-IN-1 can be used for rheumatoid arthritis (RA) research[1].

  • CAS Number

    [2413940-56-2]

  • Molecular Formula

    C27H27NO7

  • Molecular Weight

    477.51

  • Smiles

    O=C(NC1=CC=C(OC2=CC(OC)=CC=C2C(C)=O)C=C1)/C=C/C3=CC(OC)=C(OC)C(OC)=C3

  • Target

    COX; NF-κB; NO Synthase; p38 MAPK

  • Isoform

    COX-2; iNOS; NF-κB; p38 MAPK

  • Concentration

    10mM

  • Purity

    98.71

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0149489-01
5 mgQM-0149489-01
£188.51/ea		 £0.00
£188.51/ea £0.00
10 mM - 1 mLQM-0149489-02
10 mM - 1 mLQM-0149489-02
£195.80/ea		 £0.00
£195.80/ea £0.00
10 mgQM-0149489-03
10 mgQM-0149489-03
£288.14/ea		 £0.00
£288.14/ea £0.00
25 mgQM-0149489-04
25 mgQM-0149489-04
£577.31/ea		 £0.00
£577.31/ea £0.00
50 mgQM-0149489-05
50 mgQM-0149489-05
£940.60/ea		 £0.00
£940.60/ea £0.00
100 mgQM-0149489-06
100 mgQM-0149489-06
£1,556.60/ea		 £0.00
£1,556.60/ea £0.00
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NF-κB/MAPK-IN-1 [CAS 2413940-56-2]

NF-κB/MAPK-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.