Niflumic acid [CAS 4394-00-7]
Niflumic acid [CAS 4394-00-7]
SKU:QM-0158443-01
Couldn't load pickup availability
Request quote or documents
![Niflumic acid [CAS 4394-00-7]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
Niflumic acid is a calcium-activated chloride channel blocker and COX-2 inhibitor with the IC50 value of 100 nM. Niflumic acid induces apoptosis through caspase-8/Bid/Bax pathway in lung cancer cells. Niflumic acide exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9. Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis[1][2][3][4][5][6][7][8].
-
CAS Number
[4394-00-7]
-
Molecular Formula
C13H9F3N2O2
-
Molecular Weight
282.22
-
Smiles
O=C(C1=CC=CN=C1NC2=CC=CC(C(F)(F)F)=C2)O
-
Target
Chloride Channel; COX
-
Isoform
COX-2
-
Purity
99.88
-
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL
-
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
-
Shipping Conditions
Room Temperature
-
Hazard Statement
H301, H413
-
Precautions
H301, H413
Related Products
- QM-0054453-01 Δ9-Tetrahydrocannabinolic acid [CAS 23978-85-0]
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0052686-01 β-Phenyl GHB (sodium) [CAS 40951-19-7]
- QM-0051720-01 β-Phenylethyl β-D-glucoside [CAS 18997-54-1]
- QM-0049152-01 β-keto Phentermine (hydrochloride) [CAS 6946-08-3]
- QM-0048489-01 β-N-methylamino-L-alanine (hydrochloride) (Standard) [CAS 16012-55-8]
- QM-0022874 β-Prumycin hydrochloride [CAS 54612-74-7]
- QM-0008481-01 β-Methoxy 2C-B (hydrochloride) [CAS 98537-39-4]
- QM-0005999-01 β-Muricholic acid (Standard) [CAS 2393-59-1]
- QM-0161998-01 γ-Aminobutyric acid (Standard) [CAS 56-12-2]
Other industry favorites
- QM-0054453-01 Δ9-Tetrahydrocannabinolic acid [CAS 23978-85-0]
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0143709-01 γ-Acetylenic GABA (hydrochloride) [CAS 103451-26-9]
- QM-0178574-01 β-Sitosterol acetate, 40% (contains Campesterol acetate) [CAS 915-05-9]
- QM-0061106-01 γ-D-Glutamylaminomethylsulfonic acid [CAS 90237-02-8]
- QM-0090052 β-Peltoboykinolic acid [CAS 24778-48-1]
- QM-0161999-01 γ-Aminobutyric acid-d6 [CAS 70607-85-1]
- QM-0162002-01 γ-Aminobutyric acid-13C4
- QM-0111443-01 β-Methylcholine (chloride) [CAS 2382-43-6]
- QM-0067514 γ-Secretase modulator 11 (hydrochloride) [CAS 2434630-30-3]
Niflumic acid [CAS 4394-00-7]
Niflumic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.