Ninerafaxstat [CAS 2254741-41-6]
Ninerafaxstat [CAS 2254741-41-6]
SKU:QM-0146763-01
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Product Details
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Description
Ninerafaxstat (IMB-1018972) is a novel orally active cardiac mitochondrial drug that restores myocardial energy homeostasis. Ninerafaxstat competitively inhibits 3-ketoacyl-CoA thiolase (3-KAT) to partially suppress fatty acid oxidation, and shifts cardiac energy metabolism from free fatty acid oxidation to glucose oxidation, regulating myocardial substrate utilization and thereby improving cardiac efficiency. Ninerafaxstat can be used for research on cardiovascular diseases[1][2].
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CAS Number
[2254741-41-6]
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Molecular Formula
C22H29N3O5
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Molecular Weight
415.48
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Smiles
O=C(C1=CC=CN=C1)OCCN2CCN(CC2)CC3=CC=C(C(OC)=C3OC)OC
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Target
Mitochondrial Metabolism
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Purity
99.14
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Ninerafaxstat [CAS 2254741-41-6]
Ninerafaxstat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.