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NPS-2143 (Standard) [CAS 284035-33-2]

NPS-2143 (Standard) [CAS 284035-33-2]

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SKU:QM-0001664

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  • Description

    NPS-2143 (Standard) is the analytical standard of NPS-2143. This product is intended for research and analytical applications. NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor[1][2].

  • CAS Number

    [284035-33-2]

  • Molecular Formula

    C24H25ClN2O2

  • Molecular Weight

    408.92

  • Smiles

    N#CC1=C(OC[C@@H](CNC(C)(CC2=CC=C3C=CC=CC3=C2)C)O)C=CC=C1Cl

  • Target

    CaSR; Reference Standards

  • Shipping Conditions

    Room temperature

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NPS-2143 (Standard) [CAS 284035-33-2]

NPS-2143 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.