OATD-02 (hydrochloride)
OATD-02 (hydrochloride)
SKU:QM-0151616-01
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Product Details
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Description
OATD-02 hydrochloride is the hydrochloride salt form of OATD-02. OATD-02 hydrochloride an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1), respectively. OATD-02 hydrochloride bolishes tumor immunosuppression induced by both arginases. OATD-02 hydrochloride can be used for melanoma study[1].
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Molecular Formula
C12H26BClN2O4
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Molecular Weight
308.61
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Smiles
N[C@]1(C(O)=O)C[C@H](CCB(O)O)CC[C@H]1CN(C)C.[H]Cl
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Target
Arginase
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Purity
99.88
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Solubility
H2O : 250 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
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Shipping Conditions
Blue Ice
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OATD-02 (hydrochloride)
OATD-02 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.