Olanzapine-d3 [CAS 786686-79-1]
Olanzapine-d3 [CAS 786686-79-1]
SKU:QM-0148530-01
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Product Details
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Description
Olanzapine-d3 is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM) . Olanzapine is an atypical antipsychotic[1][2].
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CAS Number
[786686-79-1]
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Molecular Formula
C17H17D3N4S
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Molecular Weight
315.45
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Smiles
[2H]C(N1CCN(C2=NC3=CC=CC=C3NC4=C2C=C(C)S4)CC1)([2H])[2H]
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Target
5-HT Receptor; Adrenergic Receptor; Apoptosis; Autophagy; Dopamine Receptor; mAChR; Mitophagy
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Isoform
5-HT2 Receptor;5-HT6 Receptor; D3 Receptor; mAChR1
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Purity
99.09
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Solubility
10 mM in DMSO|DMSO : 20mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301-H317-H319
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Precautions
P261-P264-P270-P272-P280-P302+P352-P305+P351+P338-P330-P362+P364-P405-P501
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Olanzapine-d3 [CAS 786686-79-1]
Olanzapine-d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.