Orotic acid (zinc) [CAS 68399-76-8]
Orotic acid (zinc) [CAS 68399-76-8]
SKU:QM-0162158-01
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Product Details
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Description
Orotic acid (zinc), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid (zinc) is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid (zinc) can induce hepatic steatosis and hepatomegaly in rats[1][2][3].
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CAS Number
[68399-76-8]
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Molecular Formula
C5H4N2O4Zn0.5
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Molecular Weight
188.79
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Smiles
O=C(C(NC1=O)=CC(N1)=O)O.[0.5Zn]
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Target
Endogenous Metabolite; Nucleoside Antimetabolite/Analog
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Isoform
Human Endogenous Metabolite
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Purity
99.84
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Solubility
DMSO : 20 mg/mL (ultrasonic; adjust pH to 2 with 1 M HCl)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Orotic acid (zinc) [CAS 68399-76-8]
Orotic acid (zinc) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.