Osimertinib (Standard) [CAS 1421373-65-0]
Osimertinib (Standard) [CAS 1421373-65-0]
SKU:QM-0152368-01
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Product Details
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Description
Osimertinib (Standard) is the analytical standard of Osimertinib. This product is intended for research and analytical applications. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1].
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CAS Number
[1421373-65-0]
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Molecular Formula
C28H33N7O2
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Molecular Weight
499.61
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Smiles
C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O
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Target
EGFR; Reference Standards
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Purity
99.69
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Storage Conditions
4°C, sealed storage, away from light and moisture
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Osimertinib (Standard) [CAS 1421373-65-0]
Osimertinib (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.