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OTS186935 (hydrochloride)

OTS186935 (hydrochloride)

Size

QM-0140474-01

£426.65 GBP
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Product Details

  • Description

    OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochloride regulates the production of γ-H2AX in cancer cells[1].

  • Molecular Formula

    C25H26ClN5O2.8/5HCl

  • Molecular Weight

    522.31

  • Smiles

    COC1=C(Cl)C=C(C2=CN3C=CC(N4C[C@@H](NCC5=CC=NC=C5)CC4)=CC3=N2)C(OC)=C1.[H]Cl.[8/5]

  • Target

    Histone Methyltransferase

  • Isoform

    SUV39H2/KMT1B

  • Purity

    99.58

  • Solubility

    DMSO : 25 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0140474-01
5 mgQM-0140474-01
£426.65/ea		 £0.00
£426.65/ea £0.00
10 mM - 1 mLQM-0140474-02
10 mM - 1 mLQM-0140474-02
£482.54/ea		 £0.00
£482.54/ea £0.00
10 mgQM-0140474-03
10 mgQM-0140474-03
£678.15/ea		 £0.00
£678.15/ea £0.00
25 mgQM-0140474-04
25 mgQM-0140474-04
£1,305.10/ea		 £0.00
£1,305.10/ea £0.00
50 mgQM-0140474-05
50 mgQM-0140474-05
£1,806.89/ea		 £0.00
£1,806.89/ea £0.00
100 mgQM-0140474-06
100 mgQM-0140474-06
£2,497.01/ea		 £0.00
£2,497.01/ea £0.00
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OTS186935 (hydrochloride)

OTS186935 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.