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OTS514 (hydrochloride) [CAS 2319647-76-0]
OTS514 (hydrochloride) [CAS 2319647-76-0]
SKU:QM-0073975
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Product Details
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Description
OTS514 hydrochloride is a highly potent TOPK inhibitor, which inhibits TOPK kinase activity with a median inhibitory concentration (IC50) value of 2.6 nM. OTS514 hydrochloride strongly suppresses the growth of TOPK-positive cancer cells[1]. OTS514 hydrochloride induces cell cycle arrest and apoptosis[2].
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CAS Number
[2319647-76-0]
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Molecular Formula
C21H21ClN2O2S
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Molecular Weight
400.92
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Smiles
O=C1NC2=C(C(C3=CC=C([C@@H](C)CN)C=C3)=C(O)C=C2C)C4=C1SC=C4.[H]Cl
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Target
Apoptosis; TOPK
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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OTS514 (hydrochloride) [CAS 2319647-76-0]
OTS514 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.