Oxaprozin (Standard) [CAS 21256-18-8]
Oxaprozin (Standard) [CAS 21256-18-8]
SKU:QM-0158961-01
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Product Details
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Description
Oxaprozin (Standard) is the analytical standard of Oxaprozin. This product is intended for research and analytical applications. Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties[1][2].
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CAS Number
[21256-18-8]
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Molecular Formula
C18H15NO3
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Molecular Weight
293.32
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Smiles
O=C(O)CCC1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)O1
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Target
Akt; Apoptosis; COX; IKK; NF-κB; Reference Standards
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Shipping Conditions
Room temperature
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Hazard Statement
H302
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Precautions
P264-P270-P330-P501
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Oxaprozin (Standard) [CAS 21256-18-8]
Oxaprozin (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.