Paclitaxel-2′-succinate NHS ester [CAS 245110-80-9]
Paclitaxel-2′-succinate NHS ester [CAS 245110-80-9]
SKU:QM-0153683-01
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Product Details
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Description
Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy[1].
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CAS Number
[245110-80-9]
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Molecular Formula
C55H58N2O19
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Molecular Weight
1051.05
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Smiles
CC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)O)C)=O)OC(C)=O)=C([C@H](C4)OC([C@H](OC(CCC(ON5C(CCC5=O)=O)=O)=O)[C@H](C6=CC=CC=C6)NC(C7=CC=CC=C7)=O)=O)C)C)O)OC(C8=CC=CC=C8)=O)=O
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Target
Drug Derivative; Microtubule/Tubulin
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Purity
98.78
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Paclitaxel-2′-succinate NHS ester [CAS 245110-80-9]
Paclitaxel-2′-succinate NHS ester is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.