Pactimibe (sulfate) (Standard) [CAS 608510-47-0]
Pactimibe (sulfate) (Standard) [CAS 608510-47-0]
SKU:QM-0001801
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Product Details
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Description
Pactimibe (sulfate) (Standard) is the analytical standard of Pactimibe (sulfate). This product is intended for research and analytical applications. Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 μM and 3.0 μM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 μM, 2.7 μM, 4.7 μM in the liver, macrophages and THP-1 cells, respectively[1]. Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 μM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 μM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity[2].
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CAS Number
[608510-47-0]
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Molecular Formula
C25H40N2O3.1/2H2O4S
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Molecular Weight
465.65
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Smiles
O=C(O)CC1=C(C)C2=C(N(CCCCCCCC)CC2)C(NC(C(C)(C)C)=O)=C1C.O=S(O)(O)=O.[1/2]
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Target
Acyltransferase; Reference Standards
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Shipping Conditions
Room temperature
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Pactimibe (sulfate) (Standard) [CAS 608510-47-0]
Pactimibe (sulfate) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.