Panobinostat-d4 [CAS 1185237-51-7]
Panobinostat-d4 [CAS 1185237-51-7]
SKU:QM-0081855-01
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Product Details
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Description
Panobinostat-d4 is the deuterium labeled Panobinostat. Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities[1][2]. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells[4]. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma[3].
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CAS Number
[1185237-51-7]
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Molecular Formula
C21H19D4N3O2
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Molecular Weight
353.45
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Smiles
O=C(NO)/C=C/C1=CC=C(CNCCC2=C(C)NC3=C2C([2H])=C([2H])C([2H])=C3[2H])C=C1
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Target
Apoptosis; Autophagy; HDAC; HIV
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Panobinostat-d4 [CAS 1185237-51-7]
Panobinostat-d4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.