Papiliocin
Papiliocin
SKU:QM-0025316
Request quote or documents
Product Details
-
Description
Papiliocin is a potent peptide antibiotic with both anti-inflammatory and antibacterial activities. Papiliocin is primarily active against Gram-negative bacteria. Papiliocin exhibits strong anti-inflammatory activity against cell, exerting its anti-inflammatory activity by inhibiting the production of NO and the secretion of TNF-α and MIP-2. Papiliocin participates in the innate defense response mechanism by inhibiting the Toll-like receptor pathway and NF-κB. Papiliocin induces apoptosis in fungal cells and increases the total level of intracellular ROS. Papiliocin acts as an effective antiseptic peptide in sepsis models. Papiliocin is useful in anti-inflammatory and antibacterial research[1][3].
-
Molecular Formula
C183H314N56O44
-
Molecular Weight
4002.8
-
Smiles
O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](C)C(NCC(N4[C@@H](CCC4)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
-
Target
Antibiotic; Apoptosis; Bacterial; Fungal; Interleukin Related; NF-κB; NO Synthase; Reactive Oxygen Species (ROS) ; TNF Receptor; Toll-like Receptor (TLR)
-
Isoform
IL-1; IL-6; iNOS; TLR4
-
Shipping Conditions
Room temperature
Related Products
- QM-0004538-01 Zometapine [CAS 51022-73-2]
- QM-0206023-01 α-Demethylnaproxen [CAS 23981-47-7]
- QM-0151856-01 Ziapin 2 [CAS 2399497-60-8]
- QM-0127976 δ-Tocotrienol prodrug-1 [CAS 128254-90-0]
- QM-0127447-01 α-Demethylnaproxen (Standard) [CAS 23981-47-7]
- QM-0067858 Zicronapine [CAS 170381-16-5]
- QM-0059536 α-Hydroxytamoxifen [CAS 97151-02-5]
- QM-0067863 Zicronapine (fumarate) [CAS 170381-17-6]
- QM-0073738 Zoptarelin doxorubicin [CAS 139570-93-7]
- QM-0047346 Usp54 Rat Pre-designed siRNA Set A
Other industry favorites
- QM-0004538-01 Zometapine [CAS 51022-73-2]
- QM-0206023-01 α-Demethylnaproxen [CAS 23981-47-7]
- QM-0040834 Usp50 Mouse Pre-designed siRNA Set A
- QM-0039734 Usp48 Mouse Pre-designed siRNA Set A
- QM-0137353-01 USP7-IN-3 [CAS 2202738-42-7]
- QM-0149098-01 USP7-IN-9 [CAS 2444374-01-8]
- QM-0044176 Usp51 Rat Pre-designed siRNA Set A
- QM-0041331 Usp9x Rat Pre-designed siRNA Set A
- QM-0011868 USP7-IN-18 [CAS 3052223-40-9]
- QM-0011446-01 USP7 activator 1 [CAS 868940-26-5]
Papiliocin
Papiliocin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.