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PD-1/PD-L1-IN-9 (hydrochloride)
PD-1/PD-L1-IN-9 (hydrochloride)
SKU:QM-0143882-01
£401.13 GBP
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Product Details
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Description
PD-1/PD-L1-IN-9 hydrochloride is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 hydrochloride can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 hydrochloride also exhibits significant in vivo antitumor activity in a CT26 mouse model[1].
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Molecular Formula
C22H25ClN2O2
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Molecular Weight
384.9
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Smiles
CC1=C(C=CC=C1C2=CC=CC=C2)C3=NC(OC)=C(C=C3)CNCCO.[H]Cl
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Target
PD-1/PD-L1
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Purity
98.59
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Solubility
DMSO : 125 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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PD-1/PD-L1-IN-9 (hydrochloride)
PD-1/PD-L1-IN-9 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.