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PD 404182 (Standard) [CAS 72596-74-8]

PD 404182 (Standard) [CAS 72596-74-8]

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SKU:QM-0008916

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  • Description

    Paris saponin VII (Standard) is the analytical standard of Paris saponin VII. This product is intended for research and analytical applications. Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia[1].

  • CAS Number

    [72596-74-8]

  • Molecular Formula

    C11H11N3S

  • Molecular Weight

    217.29

  • Smiles

    N=C1SC2=CC=CC=C2C3=NCCCN13

  • Target

    Antibiotic; Dimethylargininase (DDAH) ; Reference Standards

  • Shipping Conditions

    Room temperature

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PD 404182 (Standard) [CAS 72596-74-8]

PD 404182 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.