Perfluorotetradecanoic acid [CAS 376-06-7]
Perfluorotetradecanoic acid [CAS 376-06-7]
SKU:QM-0049521
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Product Details
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Description
Perfluorotetradecanoic acid (PFTeDA) is a PPARγ inhibitor. Perfluorotetradecanoic acid binds to human PPARγ ligand binding domain with IC50 of 22.8 μM, Kd of 157.8 μM. Perfluorotetradecanoic acid inhibits the function of Leydig cells by inducing oxidative stress and apoptosis. Perfluorotetradecanoic acid stimulates corticosterone biosynthesis but inhibits aldosterone production[1][2][3].
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CAS Number
[376-06-7]
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Molecular Formula
C14HF27O2
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Molecular Weight
714.11
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Smiles
O=C(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(F)F)F)F)F)F)F)F)F)F)F)F)F)F)O
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Target
Apoptosis; PPAR
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Purity
98
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302+H332, H351, H360, H362, H372
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Precautions
H302+H332, H351, H360, H362, H372
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Perfluorotetradecanoic acid [CAS 376-06-7]
Perfluorotetradecanoic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.