Perfluoroundecanoic acid [CAS 2058-94-8]
Perfluoroundecanoic acid [CAS 2058-94-8]
SKU:QM-0200481-01
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Product Details
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Description
Perfluoroundecanoic acid is a perfluoroalkyl substance (PFAS) . Perfluoroundecanoic acid is an orally active oxidative stress inducer. Perfluoroundecanoic acid promotes macrophage M2 polarization, activates Wnt/β-catenin signaling and enhances β-catenin nuclear accumulation. Perfluoroundecanoic acid -induced M2 phenotype macrophage accelerates tumor progression in vitro and in vivo. Perfluoroundecanoic acid induces DNA damage, reproductive and pathophysiological dysfunctions via oxidative stress in male Swiss mice. Perfluoroundecanoic acid inhibits Leydig cell development in pubertal male rats via inducing oxidative stress and autophagy. Perfluoroundecanoic acid accelerates insulitis development in a mouse model of type 1 diabetes. Perfluoroundecanoic acid can be used for the study of ovarian cancer, type 1 diabetes and inflammation[1][2][3][4].
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CAS Number
[2058-94-8]
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Molecular Formula
C11HF21O2
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Molecular Weight
564.09
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Smiles
O=C(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(F)F)F)F)F)F)F)F)F)F)F)O
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Target
Akt; Arginase; Atg8/LC3; Autophagy; Biochemical Assay Reagents; ERK; mTOR; p62; TGF-beta/Smad; Wnt; β-catenin
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Purity
99.85
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Solubility
DMSO : 200 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302+H332, H351, H360, H362, H372
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Precautions
H302+H332, H351, H360, H362, H372
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Perfluoroundecanoic acid [CAS 2058-94-8]
Perfluoroundecanoic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.