Perphenazine (dihydrochloride) [CAS 2015-28-3]
Perphenazine (dihydrochloride) [CAS 2015-28-3]
SKU:QM-0074567
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Product Details
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Description
Perphenazine dihydrochloride is an orally active dopamine receptor and histamine-1 receptor antagonist, with Ki values of 0.56 nM (D2), 0.43 nM (D3), 6 nM (5-HT2A), respectively. Perphenazine dihydrochloride also binds to Alpha-1A adrenergic receptor. Perphenazine dihydrochloride inhibits cancer cell proliferation, and induces apoptosis. Perphenazine dihydrochloride can be used in the research of mental disease, cancer, inflammation[1][3][5].
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CAS Number
[2015-28-3]
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Molecular Formula
C21H28Cl3N3OS
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Molecular Weight
476.89
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Smiles
OCCN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(Cl)C=C24)CC1.[H]Cl.[H]Cl
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Target
5-HT Receptor; Adrenergic Receptor; Apoptosis; Autophagy; Dopamine Receptor; Histamine Receptor
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Isoform
5-HT2 Receptor; D2 Receptor; D3 Receptor; D4 Receptor; mLAG-3; MUC2; MUC3; α-1 microglobulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Perphenazine (dihydrochloride) [CAS 2015-28-3]
Perphenazine (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.