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PF-06263276 (Standard) [CAS 1421502-62-6]
PF-06263276 (Standard) [CAS 1421502-62-6]
SKU:QM-0002147
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Product Details
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Description
PF-06263276 (Standard) is the analytical standard of PF-06263276. This product is intended for research and analytical applications. PF-06263276 (PF 6263276) is a potent and selective pan-JAK inhibitor, with IC50s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1, JAK2, JAK3 and TYK2, respectively. PF-06263276 inhibits pSTAT3 and TYK2 pathway. PF-06263276 has a protective effect against ear skin inflammation[1].
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CAS Number
[1421502-62-6]
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Molecular Formula
C31H31FN8O2
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Molecular Weight
566.63
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Smiles
FC1=C(O)C=C(CC)C(C2=CC(NN=C3C4=NC5=C(CN(C(C6=NC=C(N7CCCCC7)N=C6)=O)CC5)N4)=C3C=C2)=C1
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Target
JAK; Reference Standards; STAT
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Shipping Conditions
Room temperature
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PF-06263276 (Standard) [CAS 1421502-62-6]
PF-06263276 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.