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PHD2/HDACs-IN-1 [CAS 2339867-53-5]
PHD2/HDACs-IN-1 [CAS 2339867-53-5]
SKU:QM-0065810
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Product Details
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Description
PHD2/HDACs-IN-1 is a potent PHD2/HDACs hybrid inhibitor (IC50s of 1.15 μM, 19.75 μM, 26.60 μM and 15.98 μM for PHD2, HDAC1, HDAC2 and HDAC6, respectively) . PHD2/HDACs-IN-1 is a low-toxicity renoprotective agent for research of cisplatin-induced acute kidney injury (AKI) [1].
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CAS Number
[2339867-53-5]
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Molecular Formula
C18H19N9O4
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Molecular Weight
425.4
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Smiles
O=C(C1=CN=C(N2CCC(NC(C3=CN=C(N4N=CC=C4)NC3=O)=O)CC2)N=C1)NO
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Target
HDAC; HIF/HIF Prolyl-Hydroxylase
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Isoform
HDAC1; HDAC2; HDAC6
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PHD2/HDACs-IN-1 [CAS 2339867-53-5]
PHD2/HDACs-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.