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PI3K/Akt/mTOR-IN-3 [CAS 2457245-94-0]
PI3K/Akt/mTOR-IN-3 [CAS 2457245-94-0]
SKU:QM-0067683
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Product Details
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Description
PI3K/Akt/mTOR-IN-3 (compound 3d) is a potent PI3K/AKT/mTOR inhibitor. PI3K/Akt/mTOR-IN-3 displays the inhibitory activity in MCF-7, HeLa and HepG2 cells, with IC50 values of 0.77, 1.23, and 4.57μM, respectively. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 and HeLa cells at the concentration of 4 μM. PI3K/Akt/mTOR-IN-3 induces cell apoptosis and S phase arrest[1].
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CAS Number
[2457245-94-0]
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Molecular Formula
C34H51NO2
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Molecular Weight
505.77
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Smiles
CC1(C)C(C(C[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])CC(C)(C)CC[C@@](C(NCC=C)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H])=C)=O
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Target
Akt; Apoptosis; mTOR; PI3K
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PI3K/Akt/mTOR-IN-3 [CAS 2457245-94-0]
PI3K/Akt/mTOR-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.