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PI3Kδ-IN-12
PI3Kδ-IN-12
SKU:QM-0068212
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Product Details
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Description
PI3Kδ-IN-12 (compound 13) is a PI3Kδ inhibitor (pIC50 = 5.8), with pKi values of 8.0/6.5/6.4/6.7 for PI3Kδ/γ/β/α, respectively. PI3Kδ-IN-12 can be used in the study of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD) [1].
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Molecular Formula
C20H15Cl2N5O3
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Molecular Weight
444.27
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Smiles
NC(C1=C2NC(N(C2=NC(C3=CC(O)=CC=C3)=N1)CCC4=CC=C(C(Cl)=C4)Cl)=O)=O
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Target
PI3K
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Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PI3Kδ-IN-12
PI3Kδ-IN-12 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.