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PI3Kα-IN-13 [CAS 2955529-67-4]
PI3Kα-IN-13 [CAS 2955529-67-4]
SKU:QM-0072170
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Product Details
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Description
PI3Kα-IN-13 (Compound 18a) is a PI3Kα inhibitor (IC50: 2.5 nM) . PI3Kα-IN-13 induces tumor cell apoptosis. PI3Kα-IN-13 inhibits cancer cell proliferation with IC50s of 0.75 μM (MCF-7), 3.79 μM (HCT-116), 13.71 μM (MDA-MB-231), 9.85 μM (SW620), respectively. PI3Kα-IN-13 inhibits tumor cell colony formation, migration and invasion[1].
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CAS Number
[2955529-67-4]
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Molecular Formula
C21H19N5O3
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Molecular Weight
389.41
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Smiles
NC1=NC2=CC(C3=CC=C4N=CC(N5C[C@H](OCCO6)[C@H]6C5)=NC4=C3)=CC=C2O1
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Target
PI3K
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Isoform
PI3Kα
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PI3Kα-IN-13 [CAS 2955529-67-4]
PI3Kα-IN-13 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.