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PI3Kδ-IN-14
PI3Kδ-IN-14
SKU:QM-0072143
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Product Details
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Description
PI3Kδ-IN-14 (Compound (S) -29) is a selective PI3Kδ inhibitor (IC50: 0.8 nM, Kd: 84.8 nM) . PI3Kδ-IN-14 binds to the ATP-binding site of the kinase domain of PI3Kδ. PI3Kδ-IN-14 has anti-inflammatory activity by inhibiting the PI3K/AKT pathway. PI3Kδ-IN-14 ameliorates acute lung injury (ALI) [1].
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Molecular Formula
C26H20ClFN8O
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Molecular Weight
514.94
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Smiles
ClC1=CC=C2C(N(N=C2[C@@H](N3C4=C(C(C5=CC(F)=C(C=C5)OC)=N3)C(N)=NC=N4)C)C6=CC=CN=C6)=C1
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Target
PI3K
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PI3Kδ-IN-14
PI3Kδ-IN-14 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.