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PI3Kα-IN-15 [CAS 2893920-80-2]
PI3Kα-IN-15 [CAS 2893920-80-2]
SKU:QM-0072859
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Product Details
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Description
PI3Kα-IN-15 is a potent PI3Kα inhibitor with an IC50 of 0.15 μM. PI3Kα-IN-15 also has acceptable anti-proliferative activity (inhibits SKOV-3, T47D, NCI-H1975, NCI-H460, and MCF-7 growth with IC50 values of 26.6 μM, 7.9 μM, 32.1 μM, 17.7 μM, and 9.4 μM, respectively. PI3Kα-IN-15 can be used for cancer research[1].
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CAS Number
[2893920-80-2]
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Molecular Formula
C25H24FN5O4S
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Molecular Weight
509.55
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Smiles
O=S(C1=CC=C(F)C=C1)(NC2=CC(C3=CC(C)=CN4C3=NC(C(N5CCCC5)=O)=C4)=CN=C2OC)=O
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Target
PI3K
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PI3Kα-IN-15 [CAS 2893920-80-2]
PI3Kα-IN-15 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.