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PI3Kδ-IN-20
PI3Kδ-IN-20
SKU:QM-0097010
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Product Details
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Description
PI3Kδ-IN-20 (compound (S) -36) is a potent inhibitor of PI3Kδ, with the IC50 of 6.4 nM. PI3Kδ-IN-20 has oral bioactivity. PI3Kδ-IN-20 shows significant suppression of cell proliferation and remarkable induction of apoptosis both in vitro and in vivo[1].
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Molecular Formula
C20H17ClN8
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Molecular Weight
404.86
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Smiles
CC1=NN([C@H](C2=NN(C3=CC(Cl)=CC=C23)C4=CC=NC=C4)C)C5=C1C(N)=NC=N5
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Target
PI3K
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Isoform
PI3Kδ
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PI3Kδ-IN-20
PI3Kδ-IN-20 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.