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PI3Kδ-IN-22
PI3Kδ-IN-22
SKU:QM-0099993
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Product Details
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Description
PI3Kδ-IN-22 (Compound 26) is a selective inhibitor for PI3Kδ with pKi of 9.3. PI3Kδ-IN-22 inhibits PI3Kδ-AKT signaling pathway in THP-1 cells, with pIC50 of 9.4. PI3Kδ-IN-22 exhibits good pharmacokinetic characters in rats[1].
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Molecular Formula
C27H35FN8O4S
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Molecular Weight
586.68
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Smiles
O=C1N(C(C)(C)C)N=CC([C@@H](N2N=C(C3=CC(F)=CC(O)=C3)C4=C2N=CN=C4N)C)=C1SCCN(CCO)CCO
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Target
PI3K
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Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
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Shipping Conditions
Room temperature
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PI3Kδ-IN-22
PI3Kδ-IN-22 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.