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PI3Kδ-IN-24 [CAS 3051829-20-7]
PI3Kδ-IN-24 [CAS 3051829-20-7]
SKU:QM-0012754
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Product Details
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Description
PI3Kδ-IN-24 is a selective PI3Kδ inhibitor (IC50 = 0.1 nM) . PI3Kδ-IN-24 exhibits significant antiproliferative effects against PI3Kδ-overexpressing cancer cell lines. PI3Kδ-IN-24 reduces p-AKT levels and induces cell cycle arrest and apoptosis in tumor cells. PI3Kδ-IN-24 is useful in cancer research, such as diffuse large B-cell lymphoma (DLBCL) [1].
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CAS Number
[3051829-20-7]
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Molecular Formula
C28H29N7O4
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Molecular Weight
527.57
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Smiles
COC1=C(C=C(C2=CC=C3N=CN=C(C3=N2)N[C@@H](C)C(N4CCN(CC4)C)=O)C=N1)C(OC5=CC=CC=C5)=O
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Target
Akt; Apoptosis; PI3K
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Isoform
PI3Kα; PI3Kγ; PI3Kδ
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Shipping Conditions
Room temperature
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PI3Kδ-IN-24 [CAS 3051829-20-7]
PI3Kδ-IN-24 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.