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PI3Kα-IN-26

PI3Kα-IN-26

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SKU:QM-0013782

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  • Description

    PI3Kα-IN-26 (Compound 11e) is a PI3Kα inhibitor with an IC50 of 75.31 nM. PI3Kα-IN-26 has a broad-spectrum anticancer activity, such as leukemia, colon and breast cancer, without significant cytotoxic effect on the normal Vero cells (mean IC50s of 2.74, 3.50, 3.34 and 85.29 μM, respectively) [1].

  • Molecular Formula

    C24H20ClN3O3S2

  • Molecular Weight

    498.02

  • Smiles

    O=C1/C(S/C(N1C2=CC=CC=C2)=N\CCNS(=O)(C3=CC=CC=C3)=O)=C\C4=CC=C(C=C4)Cl

  • Target

    CDK; PI3K

  • Isoform

    CDK2; CDK8; PI3Kα

  • Shipping Conditions

    Room temperature

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PI3Kα-IN-26

PI3Kα-IN-26 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.