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PI3K-IN-47
PI3K-IN-47
SKU:QM-0068426
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Quantity
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Product Details
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Description
PI3K-IN-47 (Compound 27) is a bivalent PI3K inhibitor (IC50: 0.44 nM for PI3Kα, 7.18 nM, 13.92 nM, 22.83 nM for PI3Kβ, PI3Kγ, PI3Kδ) . PI3K-IN-47 induces cell cycle arrest in G1 phase, inhibits colony formation and cell migration. PI3K-IN-47 inhibits tumor growth in HGC-27 xenograft mice[1].
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Molecular Formula
C50H46F4N8O8S2
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Molecular Weight
1027.07
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Smiles
CC1=C2C=C(C3=CN=C(OC)C(NS(C4=CC=C(F)C=C4F)(=O)=O)=C3)C=C(OCCCCCCCCOC5=CC(C6=CN=C(OC)C(NS(C7=CC=C(F)C=C7F)(=O)=O)=C6)=CC8=C(C)N=CN=C58)C2=NC=N1
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Target
PI3K
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PI3K-IN-47
PI3K-IN-47 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.