Pitavastatin [CAS 147511-69-1]
Pitavastatin [CAS 147511-69-1]
SKU:QM-0157569-01
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Product Details
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Description
Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects[1][2][3][8].
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CAS Number
[147511-69-1]
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Molecular Formula
C25H24FNO4
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Molecular Weight
421.46
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Smiles
O=C(O)C[C@H](O)C[C@H](O)/C=C/C1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4
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Target
Apoptosis; Autophagy; HMG-CoA Reductase (HMGCR) ; Mitophagy
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Purity
99.83
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Pitavastatin [CAS 147511-69-1]
Pitavastatin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.