Pitavastatin (Calcium) [CAS 147526-32-7]
Pitavastatin (Calcium) [CAS 147526-32-7]
SKU:QM-0157568-01
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Product Details
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Description
Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects[1][2][3][8].
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CAS Number
[147526-32-7]
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Molecular Formula
C25H23FNO4.1/2Ca
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Molecular Weight
440.49
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Smiles
O=C([O-])C[C@H](O)C[C@H](O)/C=C/C1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4.[0.5Ca2+]
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Target
Apoptosis; Autophagy; HMG-CoA Reductase (HMGCR) ; Mitophagy
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Purity
99.89
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Solubility
DMSO : ≥ 50 mg/mL
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Pitavastatin (Calcium) [CAS 147526-32-7]
Pitavastatin (Calcium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.