Pitavastatin-d4-1 (sodium)
Pitavastatin-d4-1 (sodium)
SKU:QM-0017977-01
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Product Details
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Description
Pitavastatin-d4-1 (NK-104-d4-1) sodium is the deuterium labeled Pitavastatin sodium. Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects[1][2][3][4].
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Molecular Formula
C25H19D4FNNaO4
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Molecular Weight
447.47
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Smiles
FC(C([2H])=C1[2H])=C([2H])C([2H])=C1C2=C(/C=C/[C@@H](O)C[C@@H](O)CC(O[Na])=O)C(C3CC3)=NC4=C2C=CC=C4
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Target
Apoptosis; Autophagy; HMG-CoA Reductase (HMGCR) ; Isotope-Labeled Compounds; Mitophagy
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Purity
99.22
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Pitavastatin-d4-1 (sodium)
Pitavastatin-d4-1 (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.