Pitavastatin-d4 (hemicalcium)
Pitavastatin-d4 (hemicalcium)
SKU:QM-0157572-01
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Product Details
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Description
Pitavastatin-d4 (hemicalcium) is deuterium labeled Pitavastatin (Calcium) . Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity[1][2][3].
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Molecular Formula
C25H19D4FNO.1/2Ca2+
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Molecular Weight
444.52
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Smiles
O=C([O-])C[C@H](O)C[C@H](O)/C=C/C1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4C([2H])([2H])C4([2H])[2H].[Ca+2].[1/2]
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Target
Apoptosis; Autophagy; HMG-CoA Reductase (HMGCR) ; Isotope-Labeled Compounds; Mitophagy
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Pitavastatin-d4 (hemicalcium)
Pitavastatin-d4 (hemicalcium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.