Pitavastatin-d5 (sodium)
Pitavastatin-d5 (sodium)
SKU:QM-0074729
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Product Details
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Description
Pitavastatin-d5 (sodium) is the deuterium labeled Pitavastatin sodium. Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity.
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Molecular Formula
C25H18D5FNNaO4
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Molecular Weight
448.47
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Smiles
O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4([2H])C([2H])([2H])C4([2H])[2H]
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Target
Apoptosis; Autophagy; HMG-CoA Reductase (HMGCR) ; Mitophagy
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Purity
99.53
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Solubility
10 mM in DMSO|DMSO : 100mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, stored under nitrogen)
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Shipping Conditions
Blue Ice
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Pitavastatin-d5 (sodium)
Pitavastatin-d5 (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.