Pitavastatin (sodium) [CAS 574705-92-3]
Pitavastatin (sodium) [CAS 574705-92-3]
SKU:QM-0074730
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Product Details
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Description
Pitavastatin (NK-104) sodium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin sodium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin sodium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin sodium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects[1][2][3][8].
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CAS Number
[574705-92-3]
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Molecular Formula
C25H23FNNaO4
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Molecular Weight
443.44
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Smiles
O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C2=CC=C(C=C2)F)C3=C(C=CC=C3)N=C1C4CC4
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Target
Apoptosis; Autophagy; HMG-CoA Reductase (HMGCR) ; Mitophagy
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Pitavastatin (sodium) [CAS 574705-92-3]
Pitavastatin (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.