PJAK2 (1001-1013) [CAS 1259928-08-9]
PJAK2 (1001-1013) [CAS 1259928-08-9]
SKU:QM-0181286-01
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Product Details
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Description
PJAK2 (1001-1013) is a cell-penetrating peptide that corresponds to the activation loop of JAK2 tyrosine kinase and functions as a SOCS1/3antagonist. pJAK2 (1001-1013) blocks SOCS1-mediated negative regulation of immune function, and enhances the biological activity of cytokines such as IFNγ and IL6. pJAK2 (1001-1013) inhibits the replication of a broad range of viruses and exerts dose-dependent protective efficacy against lethal viral infections. pJAK2 (1001-1013) can be used for the study of immune regulation and infection[1][2][3].
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CAS Number
[1259928-08-9]
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Molecular Formula
C76H118N17O26P
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Molecular Weight
1716.82
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Smiles
O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N2[C@H](C(O)=O)CCC2)=O)=O)=O)=O)=O)[C@@H](NC([C@H](CCC(O)=O)NC([C@H](CCCCN)NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H]3N(C([C@H](CC(C)C)N)=O)CCC3)=O)=O)=O)=O)=O)CC4=CC=C(OP(O)(O)=O)C=C4
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Target
IFNAR; Interleukin Related; JAK
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Purity
99.89
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Solubility
DMSO : 1.89 mg/mL (ultrasonic; adjust pH to 2 with 1 M HCl)
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Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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PJAK2 (1001-1013) [CAS 1259928-08-9]
PJAK2 (1001-1013) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.