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PLX5622 (hemifumarate)
PLX5622 (hemifumarate)
SKU:QM-0138292-01
£200.66 GBP
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Product Details
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Description
PLX5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor (IC50=0.016 μM; Ki=5.9 nM) . PLX5622 hemifumarate allows for extended and specific microglial elimination, preceding and during pathology development. PLX5622 hemifumarate demonstrates desirable PK properties in varies animals[1][2].
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Molecular Formula
C23H21F2N5O3
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Molecular Weight
453.45
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Smiles
COC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2.O=C(O)/C=C/C(O)=O
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Target
C-Fms
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Concentration
10mM
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Purity
99.93
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Solubility
DMSO : 110 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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PLX5622 (hemifumarate)
PLX5622 (hemifumarate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.