Polyinosinic-polycytidylic acid (potassium) [CAS 31852-29-6]
Polyinosinic-polycytidylic acid (potassium) [CAS 31852-29-6]
SKU:QM-0144898
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Product Details
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Description
Polyinosinic-polycytidylic acid potassium (Poly (I:C) potassium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I) -like receptors (RIG-I and MDA5) . Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid potassium can directly trigger cancer cells to undergoApoptosis[1][2][3].
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CAS Number
[31852-29-6]
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Molecular Formula
(C10H13N4O8P) x. (C9H14N3O8P) x.xK
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Smiles
O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N2C3=C(C(N=CN3)=O)N=C2.O[C@@H]4[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]4N5C(N=C(C=C5)N)=O.[x].[x]
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Target
Apoptosis; Toll-like Receptor (TLR)
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Isoform
TLR3
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Polyinosinic-polycytidylic acid (potassium) [CAS 31852-29-6]
Polyinosinic-polycytidylic acid (potassium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.