Polyinosinic-polycytidylic acid (sodium) [CAS 42424-50-0]
Polyinosinic-polycytidylic acid (sodium) [CAS 42424-50-0]
SKU:QM-0145187-01
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Product Details
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Description
Polyinosinic-polycytidylic acid (Poly (I:C) ) sodium is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I) -like receptors (RIG-I and MDA5) . Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis[1][2].
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CAS Number
[42424-50-0]
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Molecular Formula
(C10H13N4O8P) x. (C9H14N3O8P) x.xNa
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Smiles
O[C@H]1[C@@H](O[C@H](COP(O)(O)=O)[C@H]1O)N2C3=C(C(NC=N3)=O)N=C2.O[C@H]4[C@H](N5C(N=C(N)C=C5)=O)O[C@H](COP(O)(O)=O)[C@H]4O.[x].[x].[Na].[x]
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Target
Apoptosis; Toll-like Receptor (TLR)
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Isoform
TLR3
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Purity
99
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Solubility
H2O : 10 mg/mL (ultrasonic; warming)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Polyinosinic-polycytidylic acid (sodium) [CAS 42424-50-0]
Polyinosinic-polycytidylic acid (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.